I wish I was a dab hand at grafix, however I'll try to paint a picture with words. The old antipsychotics worked by blocking dopamine receptors, the new ones do the same but also do some stuff to the seretonin sites too. First off lets talk about a neurone simplified it consists of a big roundish blob called the cell body and a long stalk called an axon. On the cell bodies surface are tree like structures called dendrites these are in addition to the axon. Now, lets talk about 2 of these neurons (nerve cells) the axon from one nerve cell ALMOST connects to the dendrites of the next nerve cell. I say almost because theres a tiny gap called a synapse. The synapse is where the chemical messengers such as dopomine pass a signal from the end of the axon to the tip(s) of a dendrite. Now different synapses around the brain have different chemical messengers, this is because the brain is awash with all sorts of hormones and "neurotransmitters"(chemical messangers) and the dendrite needs to know that the message it gets comes from the right place. When the second cell gets enough dopamine it "fires" sends an electical impulse down the axon which makes it release neurotransmitters down to the next cell on the network. Now lets take a look at the dendrites. If you taks APs (anti Psychotics) they are chemicals that fit into the receptors on the dendrites and stop it receiving. This effectively shuts down all downstream communications on the network. However the brain is a clever old thing and says hang on a sec ~I havent heard from charlie lately, so a tiny reverse synaptic transfer occurs from cell 3 in this sequence that tells cell 2 hey mat cant you grow some more dendrites you seem to be getting a bit deaf. Cell 2 says oh yeah, I've been oversleeping a bit wheres my mate cell 1 he usaully has a chat hasent been in touch for ages. So cell 2 grows more dendrites to make up for the fact that most of them are clogged up with AP shit. So you need more and more APs to clog up more and more receptors. THats why you shouldn't give APs to normaloes cause it'll send them mad, by cuasing them to become hypersensitive to dopamine. It's also why theres no cure cause the treatment makes you worse in the long run. But we're schizos, so it dosent matter fuck, if we get madder 'cause they can just up thier AP crap as often as they like until they shoot your liver, or your brain gives out completely and you get tardith dementia. By which time your mum and dad are dead and they can get one more fuckhead in a body bag and stop them sucking off the state. On their way home they laugh away in thier mercedes "Fooled them suckers, silly buggers don't realise I'm cuasing all the symptoms. My, this is the gavy train, I think I'll put this weeks xs in elly lilly." -- WARNING! When trying to withdraw from many psychiatric drugs, patients can develop serious and even life-threatening emotional and physical reactions. In short, it is dangerous not only to start taking psychiatric drugs but also can be hazardous to stop taking them. Therefore, withdrawal from psychiatric drugs should be done under clinical supervision. Principles of drug withdrawal are discussed in Your Drug May Be Your Problem: How and Why to Stop Taking Psychiatric Medications. information on Prozac and Prozac-like drugs can be found in Talking Back to Prozac by Peter R. Breggin, M.D. and Ginger Ross Breggin. DSM IV is the fabrication upon which psychiatry seeks acceptance by medicine in general. Insiders know it is more a political than scientific document. To its credit it says so --Loren R. Mosher, M.D.